微卫星及其在群体遗传学研究中的应用。

Microsatellites and their application to population genetic studies.

作者信息

Bruford M W, Wayne R K

机构信息

Conservation Genetics Group, Institute of Zoology, Regent's Park, London, UK.

出版信息

Curr Opin Genet Dev. 1993 Dec;3(6):939-43. doi: 10.1016/0959-437x(93)90017-j.

DOI:10.1016/0959-437x(93)90017-j

PMID:8118220

Abstract

Microsatellites may soon become the markers of choice for molecular population genetic studies. However, our knowledge of these simple repetitive sequences and how they evolve in natural populations is far from complete. We highlight some recent results of population studies and advances in our ability to interpret some of the allele frequency distributions that we are beginning to observe.

摘要

微卫星可能很快会成为分子群体遗传学研究的首选标记。然而，我们对这些简单重复序列及其在自然群体中如何进化的了解还远远不够完整。我们着重介绍了一些群体研究的最新成果，以及我们在解读一些开始观察到的等位基因频率分布方面能力的进展。