Muir D C, Jadon N, Julian J A, Roberts R S
McMaster University, Health Sciences Center, Hamilton, Ontario.
Occup Environ Med. 1994 Jan;51(1):19-22. doi: 10.1136/oem.51.1.19.
The risk of death due to cancer of the nose or lung was studied in nickel sinter plant workers during the period after they left the sintering operations. It was found that the excess risk of death from both diseases continued for many years after leaving the sinter plant. No effect of age at first exposure could be found. Possible explanations for the continued risk include an irreversible cellular change or the persistence of carcinogenic nickel compounds in the mucosa.
对镍烧结厂工人离开烧结作业后的一段时间内,因鼻癌或肺癌导致的死亡风险进行了研究。结果发现,离开烧结厂后,这两种疾病导致的额外死亡风险持续了许多年。未发现首次接触时的年龄有任何影响。持续存在风险的可能解释包括不可逆的细胞变化或致癌镍化合物在黏膜中的持续存在。