Shirane R, Satoh S, Ogawa A, Yoshimoto T, Maruoka S
Division of Neurosurgery, Tohoku University School of Medicine, Sendai City, Japan.
Childs Nerv Syst. 1993 Dec;9(8):443-7. doi: 10.1007/BF00393545.
Cerebral blood flow in seven infants with extracerebral fluid collections was investigated using single photon emission computed tomography (SPECT) with 123I-N-isopropyl-p-iodoamphetamine. Early and delayed SPECT imaging was carried out. Areas of hypoperfusion were observed in five cases. The watershed zone of the major cerebral arteries or the territory of the anterior cerebral arteries were common areas of low perfusion. The hypoperfusion area was redistributed in two cases with intracranial hypertension. Subduroperitoneal shunts produced improvement of clinical symptoms in these cases. Hypoperfusion without redistribution was observed in three patients. In these areas, permanent tissue damage caused by a primary disease existed. Normal circulation patterns were observed in two patients. They showed normal development and follow-up CT revealed a decrease in the size of the extracerebral fluid collection. Measurement of regional cerebral blood flow may be helpful in considering surgical indications and in following up extracerebral fluid collection in infants.
采用¹²³I-N-异丙基-p-碘安非他明单光子发射计算机断层扫描（SPECT）对7例伴有脑外积液的婴儿的脑血流量进行了研究。进行了早期和延迟SPECT成像。5例观察到灌注不足区域。大脑主要动脉的分水岭区或大脑前动脉的供血区域是常见的低灌注区域。2例颅内高压患者的灌注不足区域发生了重新分布。在这些病例中，硬膜下腹腔分流术使临床症状得到改善。3例患者观察到无重新分布的灌注不足。在这些区域，存在由原发性疾病引起的永久性组织损伤。2例患者观察到正常的循环模式。他们发育正常，随访CT显示脑外积液体积减小。测量局部脑血流量可能有助于考虑手术指征和对婴儿脑外积液进行随访。
