Ziedonis D M, Rayford B S, Bryant K J, Rounsaville B J
Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519.
Hosp Community Psychiatry. 1994 Jan;45(1):43-9. doi: 10.1176/ps.45.1.43.
Few diagnostic studies have reported rates of psychiatric comorbidity among cocaine addicts according to race. This study examines psychiatric comorbidity in African-American and white cocaine addicts.
Rates of psychiatric comorbidity were assessed in 263 cocaine addicts seeking substance abuse treatment. The sample included 163 non-Hispanic whites and 100 African Americans. Diagnoses were based on patient interviews using the Schedule for Affective Disorders and Schizophrenia-Lifetime Version (SADS-L). The SADS-L was supplemented to include DSM-III-R criteria for substance abuse or dependence and other psychiatric diagnoses and DSM-III criteria for attention deficit disorder.
Overall, 55.7 percent of the cocaine addicts met Research Diagnostic Criteria for a current psychiatric diagnosis, and 73.5 percent met criteria for a lifetime psychiatric diagnosis. Whites and African Americans did not differ significantly in overall psychiatric comorbidity. However, whites had significantly higher rates of life-time major depression, alcohol dependence, attention deficit disorder, and conduct disorder. African-American addicts, particularly women, were more likely to meet criteria for a current diagnosis of phobia.
Psychiatric comorbidity is common among cocaine addicts, and the rates for specific disorders vary by race. Differences in current and lifetime rates should be noted. Cocaine addicts seeking treatment should be assessed for comorbid alcohol dependence and other psychiatric disorders, including anxiety, affective, and personality disorders.
很少有诊断研究报告过按种族划分的可卡因成瘾者中精神疾病共病率。本研究调查非裔美国人和白人可卡因成瘾者中的精神疾病共病情况。
对263名寻求药物滥用治疗的可卡因成瘾者的精神疾病共病率进行了评估。样本包括163名非西班牙裔白人以及100名非裔美国人。诊断基于使用情感障碍和精神分裂症终身版访谈表(SADS-L)对患者进行的访谈。SADS-L进行了补充,纳入了《精神疾病诊断与统计手册》第三版修订版(DSM-III-R)中关于药物滥用或依赖以及其他精神疾病诊断的标准,以及DSM-III中关于注意力缺陷障碍的标准。
总体而言,55.7%的可卡因成瘾者符合当前精神疾病诊断的研究诊断标准,73.5%符合终身精神疾病诊断标准。白人和非裔美国人在总体精神疾病共病方面无显著差异。然而,白人在终身重度抑郁症、酒精依赖、注意力缺陷障碍和品行障碍方面的发生率显著更高。非裔美国成瘾者,尤其是女性,更有可能符合当前恐惧症诊断标准。
精神疾病共病在可卡因成瘾者中很常见,特定疾病的发生率因种族而异。应注意当前和终身发生率的差异。对寻求治疗的可卡因成瘾者应评估其是否合并酒精依赖及其他精神疾病,包括焦虑症、情感障碍和人格障碍。