van de Glind Geurt, Van Emmerik-van Oortmerssen Katelijne, Carpentier Pieter Jan, Levin Frances R, Koeter Maarten W J, Barta Csaba, Kaye Sharlene, Skutle Arvid, Franck Johan, Konstenius Maija, Bu Eli-Torild, Moggi Franz, Dom Geert, Demetrovics Zolt, Fatséas Mélina, Schillinger Arild, Kapitány-Fövény Máté, Verspreet Sofie, Seitz Andrea, Johnson Brian, Faraone Stephen V, Ramos-Quiroga J Antoni, Allsop Steve, Carruthers Susan, Schoevers Robert A, van den Brink Wim
Trimbos-instituut and ICASA Foundation, Utrecht, The Netherlands; Amsterdam Institute for Addiction research, Department of Psychiatry, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.
Int J Methods Psychiatr Res. 2013 Sep;22(3):232-44. doi: 10.1002/mpr.1397. Epub 2013 Sep 11.
Attention deficit/hyperactivity disorder (ADHD) is an increasingly recognized comorbid condition in subjects with substance use disorders (SUDs). This paper describes the methods and study population of the International ADHD in Substance Use Disorders Prevalence (IASP) study. Objectives of the IASP are to determine the prevalence of ADHD in adult treatment seeking patients with SUD in different countries and SUD populations, determine the reliability and validity of the Adult ADHD Self-report Scale V 1.1 (ASRS) as ADHD screening instrument in SUD populations, investigate the comorbidity profile of SUD patients with and without ADHD, compare risk factors and protective factors in SUD patients with and without a comorbid diagnosis of ADHD, and increase our knowledge about the relationship between ADHD and the onset and course of SUD. In this cross-sectional, multi-centre two stage study, subjects were screened for ADHD with the ASRS, diagnosed with the Conner's Adult ADHD Diagnostic Interview for DSM-IV (CAADID), and evaluated for SUD, major depression, bipolar disorder, anti social personality disorder and borderline personality disorder. Three thousand five hundred and fifty-eight subjects from 10 countries were included. Of these 40.9% screened positive for ADHD. This is the largest international study on this population evaluating ADHD and comorbid disorders.
注意缺陷/多动障碍（ADHD）在物质使用障碍（SUDs）患者中是一种越来越被认识到的共病情况。本文描述了物质使用障碍中注意缺陷/多动障碍国际患病率（IASP）研究的方法和研究人群。IASP的目标是确定不同国家和物质使用障碍人群中寻求治疗的成年物质使用障碍患者的ADHD患病率，确定成人ADHD自陈量表V 1.1（ASRS）作为物质使用障碍人群中ADHD筛查工具的可靠性和有效性，调查有和没有ADHD的物质使用障碍患者的共病情况，比较有和没有共病ADHD诊断的物质使用障碍患者的危险因素和保护因素，并增加我们对ADHD与物质使用障碍的发病及病程之间关系的认识。在这项横断面、多中心两阶段研究中，使用ASRS对受试者进行ADHD筛查，采用康纳斯成人ADHD DSM-IV诊断访谈（CAADID）进行诊断，并对物质使用障碍、重度抑郁症、双相情感障碍、反社会人格障碍和边缘型人格障碍进行评估。纳入了来自10个国家的3558名受试者。其中40.9%的人ADHD筛查呈阳性。这是对该人群评估ADHD及共病障碍的最大规模国际研究。
