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接受可卡因使用障碍应急管理的美沙酮维持治疗女性中,HIV风险行为的种族差异。

Ethnic differences in HIV risk behaviors among methadone-maintained women receiving contingency management for cocaine use disorders.

作者信息

Barry Danielle, Weinstock Jeremiah, Petry Nancy M

机构信息

Department of Psychiatry, University of Connecticut Health Center, Farmington, CT 06030, United States.

出版信息

Drug Alcohol Depend. 2008 Nov 1;98(1-2):144-53. doi: 10.1016/j.drugalcdep.2008.06.009. Epub 2008 Aug 6.

Abstract

OBJECTIVE

To identify ethnic differences in HIV risk behaviors among cocaine using women receiving methadone maintenance for opioid dependence, and to evaluate the efficacy of contingency management (CM) for cocaine use disorders in reducing HIV risk behaviors.

METHODS

African American (N=47), Hispanic (N=47), and White women (N=29) were randomized to standard methadone treatment or standard methadone treatment plus a CM intervention. They completed the HIV Risk Behavior Scale (HRBS) indicating frequency of drug use and sexual behaviors across the lifetime, in the month before baseline, and in the 3 months following clinical trial participation. Ethnic group differences and the effect of CM on change in HIV risk behaviors between baseline and follow-up were evaluated.

RESULTS

White women reported significantly higher lifetime rates of risky drug use and sexual behaviors on the HRBS than African American women; neither group differed significantly from Hispanic women. No ethnic group differences in HIV risk behaviors were identified in the month prior to baseline. At follow-up, African American women reported fewer high-risk drug use behaviors than White or Hispanic women, and Hispanic women reported more high-risk sexual behaviors than White or African American women. CM was associated with reduction in high-risk drug use behaviors regardless of ethnicity, but did not affect high-risk sexual behaviors.

CONCLUSIONS

White women receiving methadone maintenance engage in more lifetime HIV risk behaviors than African American women. CM for cocaine use reduces risky drug use behaviors, but certain ethnic groups may benefit from additional targeted HIV prevention efforts.

摘要

目的

确定接受美沙酮维持治疗以解决阿片类药物依赖问题的可卡因使用女性中,HIV风险行为的种族差异,并评估应急管理(CM)对可卡因使用障碍在减少HIV风险行为方面的疗效。

方法

将非裔美国女性(N = 47)、西班牙裔女性(N = 47)和白人女性(N = 29)随机分为标准美沙酮治疗组或标准美沙酮治疗加CM干预组。她们完成了HIV风险行为量表(HRBS),该量表表明了一生中、基线前一个月以及参与临床试验后的3个月内药物使用和性行为的频率。评估了种族差异以及CM对基线和随访之间HIV风险行为变化的影响。

结果

白人女性在HRBS上报告的一生中危险药物使用和性行为发生率显著高于非裔美国女性;两组与西班牙裔女性相比均无显著差异。在基线前一个月未发现HIV风险行为的种族差异。在随访时,非裔美国女性报告的高风险药物使用行为少于白人或西班牙裔女性,而西班牙裔女性报告的高风险性行为多于白人或非裔美国女性。无论种族如何,CM都与高风险药物使用行为的减少有关,但不影响高风险性行为。

结论

接受美沙酮维持治疗的白人女性一生中从事的HIV风险行为比非裔美国女性更多。针对可卡因使用的CM可减少危险药物使用行为,但某些种族群体可能受益于额外的针对性HIV预防措施。

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