Galvão C E, Silva A C, Saldanha A C, Silva C M, Costa M do R, Costa J M
Departamento de Patologia, Faculdade de Medicina da Universidade Federal do Maranhão, São Luís, MA, Brasil.
Rev Soc Bras Med Trop. 1993 Apr-Jun;26(2):121-3. doi: 10.1590/s0037-86821993000200008.
The authors describe a case of a patient from Barreirinhas, MA with disseminated cutaneous leishmaniasis, who presented 58 lesions spread all over his body, with many different aspects, but ulcerative lesions were predominant. They discuss the difficulty of laboratory diagnosis in the beginning of the investigation and its therapeutics implications. The parasite isolated was identified as Leishmania viannia braziliensis using monoclonal antibodies in the fluorescent antibody test. This form of the disease is different from the diffuse cutaneous leishmaniasis found in Maranhão, due to Leishmania (Leishmania) amazonensis which is responsible for most of the cases of cutaneous leishmaniasis in our state. The possible mechanisms of lesions dissemination are discussed.
作者描述了一例来自马亚州巴雷里尼亚斯的播散性皮肤利什曼病患者，该患者全身出现58处皮损，表现形式多样，但以溃疡性皮损为主。他们讨论了调查初期实验室诊断的困难及其治疗意义。通过荧光抗体试验使用单克隆抗体鉴定出分离出的寄生虫为巴西利什曼原虫维安尼亚亚种。这种疾病形式与马拉尼昂州发现的弥漫性皮肤利什曼病不同，后者由亚马逊利什曼原虫（利什曼原虫属）引起，该原虫是我们州大多数皮肤利什曼病病例的病因。文中还讨论了皮损播散的可能机制。
