Eagleson J S, Thompson D R, Scott P G, Cramer L G, Barrick R A
Merck Research Laboratories, Rahway, NJ 07065.
Vet Parasitol. 1993 Dec;51(1-2):107-12. doi: 10.1016/0304-4017(93)90201-w.
Fifty-two field trials, involving 14,296 sheep, were conducted to confirm the efficacy and safety of ivermectin jetting fluid against blow fly strike in sheep in Australia. A total of 7143 sheep were treated by hand-jetting with a 0.03 mg ml-1 solution of ivermectin, while 7153 sheep were untreated controls. The percent reduction in the cumulative incidence of strikes within the treatment area for ivermectin-treated sheep in comparison with untreated controls, was 96.5%, 95.8% and 93.5% at 10, 12 and 13/14 weeks after treatment, respectively. There were no adverse reactions to treatment.
进行了52项田间试验,涉及14296只绵羊,以确认伊维菌素喷射液对澳大利亚绵羊蝇蛆病的疗效和安全性。共有7143只绵羊用0.03毫克/毫升的伊维菌素溶液进行手工喷射处理,而7153只绵羊为未处理的对照。与未处理的对照相比,伊维菌素处理的绵羊在处理区域内叮咬累积发病率在处理后10、12和13/14周分别降低了96.5%、95.8%和93.5%。处理没有不良反应。