Lauweryns J M, Baert J, De Loecker W
J Cell Biol. 1976 Jan;68(1):163-7. doi: 10.1083/jcb.68.1.163.
Several and various types of cells contain fine cytoplasmic filaments closely resembling the myofilaments of muscle cells (2, 18, 23, 24). In many of these cells and especially when cultured, it has been demonstrated that some of these filaments react with heavy meromyosin (HMM) in the same way as do the actin filaments of muscle cells (3, 6 7). This suggests that these filaments may be actinoid and form part of a contractile system. As fine intracytoplasmic filaments do occur in lymphatic endothelial cells (2, 14), we undertook an electron microscope investigation of their fine structure and their reaction on incubation with HMM and EDTA. We postulated that lymphatic endothelial cells possess a contractile filamentous system to which these filaments belong.
多种类型的细胞含有纤细的细胞质细丝,与肌肉细胞的肌丝极为相似(2, 18, 23, 24)。在许多这类细胞中,尤其是在培养时,已经证明其中一些细丝与重酶解肌球蛋白(HMM)的反应方式与肌肉细胞的肌动蛋白丝相同(3, 6, 7)。这表明这些细丝可能是类肌动蛋白的,并构成收缩系统的一部分。由于在淋巴管内皮细胞中确实存在纤细的胞质细丝(2, 14),我们对其精细结构以及与HMM和EDTA孵育后的反应进行了电子显微镜研究。我们推测淋巴管内皮细胞拥有一个这些细丝所属的收缩性丝状系统。