Dankert J, Schut I K
J Hyg (Lond). 1976 Feb;76(1):11-22. doi: 10.1017/s0022172400054899.
The bactericidal activity of RBA 777 has been found to vary with both the cultural and environmental test conditions against Pseudomonas aeruginosa and to a lesser extent against Staphylococcus aureus. These variations may explain certain anomalies in earlier work regarding the activity of chloroxylenol-based products. The addition of EDTA to RBA 777 has brought about an improvement in the performance against P. aeruginosa and this activity is confirmed in vivo. Previous reports have already illustrated this potential and the evaluations of the new antibacterial agent DA 136 confirms and extends these results to its performance under adverse conditions, often associated with the hospital environment.
已发现RBA 777对铜绿假单胞菌的杀菌活性会因培养和环境测试条件而有所不同，对金黄色葡萄球菌的杀菌活性差异较小。这些差异可能解释了早期关于对氯二甲苯酚类产品活性研究中的某些异常现象。在RBA 777中添加乙二胺四乙酸（EDTA）提高了其对铜绿假单胞菌的抗菌性能，且这种活性在体内得到了证实。先前的报告已经阐明了这种潜力，新型抗菌剂DA 136的评估结果证实并扩展了这些结果，表明其在通常与医院环境相关的不利条件下的性能。
