Ojajärvi J
J Hyg (Lond). 1976 Feb;76(1):75-82. doi: 10.1017/s0022172400054966.
The antibacterial effectiveness of hand antiseptics commonly used in wards was studied by laboratory and in-use tests and their acceptability assessed by means of a questionnaire passed to hospital staff. To determine the immediate and long-term antibacterial effects of the preparations the in-use tests were performed by groups of students. The greatest immediate reduction in bacterial counts on hands was obtained by products containing chlorhexidine. The long-term antibacterial effect was recorded with emulsions containing 3% hexachlorophane, 2% Irgasan CF3R or 4% chlorhexidine when used constantly on several consecutive days. Considerable discrepancies were recorded in the antibacterial effectiveness of some preparations when comparing laboratory and in-use test results. Therefore it is suggested that antiseptics should be tested by in-use tests which more closely resemble practical conditions before their use, or further trial, in hospital.
通过实验室测试和实际使用测试研究了病房常用手部抗菌剂的抗菌效果,并通过向医院工作人员发放问卷的方式评估了它们的可接受性。为确定这些制剂的即时和长期抗菌效果,实际使用测试由几组学生进行。含氯己定的产品能使手部细菌数量立即大幅减少。当连续几天持续使用含3%六氯酚、2%三氯生CF3R或4%氯己定的乳液时,可记录到长期抗菌效果。在比较实验室测试结果和实际使用测试结果时,发现一些制剂的抗菌效果存在相当大的差异。因此建议,在医院使用或进一步试验之前,抗菌剂应通过更接近实际情况的实际使用测试进行检测。