Sizun J, Prigent D, Tande D, Giroux J D, Rubio S, Alix D, de Parscau L
Service de Réanimation Pédiatrique et Néonatologie, CHRU, Brest.
Ann Pediatr (Paris). 1993 Dec;40(10):622-4.
A splenectomized three-year-old developed fulminant pneumococcal septicemia despite immunization and chemoprophylaxis. The course was rapidly fatal. Fulminant pneumococcal septicemia mainly affects splenectomized individuals and is associated with very substantial mortality. Immunization prior to splenectomy and daily prophylactic oral penicillin have partial preventive efficacy. Other useful measures include carrying a health status card and inpatient antimicrobial therapy in the event of fever. The need for these precautions should be repeatedly discussed with the child's parents and physician.
一名三岁脾切除患儿尽管已接种疫苗并进行化学预防，仍发生了暴发性肺炎球菌败血症。病程发展迅速，最终导致死亡。暴发性肺炎球菌败血症主要影响脾切除患者，死亡率极高。脾切除术前进行免疫接种以及每日预防性口服青霉素有一定的预防效果。其他有用的措施包括携带健康状况卡，以及发热时住院接受抗菌治疗。应反复与患儿家长和医生讨论采取这些预防措施的必要性。
