Jeans W D, Cole S E, Horrocks M, Baird R N
Department of Radiology, Bristol Royal Infirmary, UK.
Br J Radiol. 1994 Feb;67(794):123-8. doi: 10.1259/0007-1285-67-794-123.
137 consecutive patients with known ankle pressures and diabetic status had attempted femoro-popliteal dilatation for lower limb ischaemia in an English provincial teaching hospital. All except one were followed until failure or death to assess survival and amputation rates. Non-diabetic patients with critical limb ischaemia had a 5 year survival rate of 62.2% (SE 17.1) compared to 50.5% (SE 7.0) for claudicants, with no significant difference on logrank testing. Diabetics had a relative risk of amputation of 11.2 compared to nondiabetics. Patients with pre-treatment ankle pressures of 50 mm or less had a relative risk of amputation of 2.6 compared to those with higher resting pressures. It is concluded that angioplasty should be the treatment of first choice in critical lower limb ischaemia whenever it is technically possible. Including patients with rest pain in the critical ischaemia group does not significantly affect cumulative patency rates.
在一家英国省级教学医院,137例已知踝压和糖尿病状况的患者因下肢缺血接受了股腘动脉扩张术。除1例患者外,所有患者均随访至手术失败或死亡,以评估生存率和截肢率。重度下肢缺血的非糖尿病患者5年生存率为62.2%(标准误17.1),间歇性跛行患者为50.5%(标准误7.0),对数秩检验无显著差异。与非糖尿病患者相比,糖尿病患者的截肢相对风险为11.2。治疗前踝压为50毫米汞柱或更低的患者与静息压较高的患者相比,截肢相对风险为2.6。结论是,只要技术上可行,血管成形术应成为重度下肢缺血的首选治疗方法。将静息痛患者纳入重度缺血组对累积通畅率无显著影响。