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花生中黄曲霉抑制剂5,7-二甲氧基异黄酮的分离与鉴定

Isolation and identification of 5,7-dimethoxyisoflavone, an inhibitor of Aspergillus flavus from peanuts.

作者信息

Turner R B, Lindsey D L, Davis D D, Bishop R D

出版信息

Mycopathologia. 1975 Dec 8;57(1):39-40. doi: 10.1007/BF00431177.

DOI:10.1007/BF00431177
PMID:813148
Abstract

An inhibitor of Aspergillus flavus has been isolated form peanuts and identified as 5,7-dimethoxyisoflavone, Authentic 5,7-dimethoxyisoflavone, synthesized from benzyl-2-hydroxy-4,6 dimethoxyphenyl (3), and the isolated compound display identical ultraviolet spectra in methanol, in methanol+sodium methoxide, and in methanol+AlCl3; similar behavior in solvent extraction, column chromatography, TLC, and fungal inhibition.

摘要

已从花生中分离出一种黄曲霉菌抑制剂,并鉴定为5,7-二甲氧基异黄酮。由苄基-2-羟基-4,6-二甲氧基苯基(3)合成的纯5,7-二甲氧基异黄酮与分离出的化合物在甲醇、甲醇+甲醇钠以及甲醇+三氯化铝中显示出相同的紫外光谱;在溶剂萃取、柱色谱、薄层色谱和真菌抑制方面表现相似。

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本文引用的文献

1
Direct bioautography on thin-layer chromatograms as a method for detecting fungitoxic substances.薄层色谱上的直接生物自显影法作为检测真菌毒性物质的一种方法。
J Chromatogr. 1970 Sep 16;51(2):327-9. doi: 10.1016/s0021-9673(01)96877-3.
花生壳中 5,7-二羟基色原酮的植物毒性和抗菌活性。
J Chem Ecol. 1995 Feb;21(2):107-15. doi: 10.1007/BF02036645.
4
Effect of peanut tannin extracts on growth of Aspergillus parasiticus and aflatoxin production.花生单宁提取物对寄生曲霉生长及黄曲霉毒素产生的影响。
Mycopathologia. 1990 Jun;110(3):125-32. doi: 10.1007/BF00437535.
5
Effect of peanut tannins on percent seed colonization and in vitro growth by Aspergillus parasiticus.花生单宁对寄生曲霉在种子上的定殖百分比及体外生长的影响。
Mycopathologia. 1979 Feb 28;66(3):169-73. doi: 10.1007/BF00683966.
6
Biosynthesis of aflatoxins.黄曲霉毒素的生物合成
Bacteriol Rev. 1977 Dec;41(4):822-55. doi: 10.1128/br.41.4.822-855.1977.