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Minoxidil overdose.

作者信息

MacMillan A R, Warshawski F J, Steinberg R A

机构信息

Holy Cross Hospital-Calgary District Hospital Group, Alberta, Canada.

出版信息

Chest. 1993 Apr;103(4):1290-1. doi: 10.1378/chest.103.4.1290.

Abstract

A 52-year-old man ingested 60 ml of 2 percent topical minoxidil solution resulting in severe hypotension and tachycardia. He was resuscitated with intravenously administered crystalloid solution and treated with intravenously administered dopamine, resulting in a partial hemodynamic improvement. Further treatment with intravenously administered phenylephrine infusion resulted in resolution of hypotension. The patient suffered a non-Q-wave myocardial infarction as a result of the ingestion. The toxicity of this increasingly common preparation is profound.

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