Deture F A, Drylie D M, Kaufman H E, Centifanto Y M
J Urol. 1978 Oct;120(4):449-51. doi: 10.1016/s0022-5347(17)57225-0.
Semen from 30 healthy male subjects with recurrent infections with herpesvirus type 2 was obtained when subjects were free of lesions and surveyed by tissue culture for an infectious virus in an attempt to elucidate the transmission of this disease. Inclusion bodies compatible with herpesvirus were found in tissue cultures of semen from 2 participants but an infectious virus could not be cultured directly from any sample. The data suggest that herpevirus type 2 is not ubiquitous in semen of male subjects with recurrent genital infections. The possible role of seminal inhibitors and a defective virus in causing the observed results is discussed, as are the current theories of herpesvirus type 2 transmission.
从30名患有复发性2型疱疹病毒感染的健康男性受试者身上采集精液，采集时受试者无皮损，通过组织培养检测感染性病毒，以试图阐明该疾病的传播情况。在2名参与者的精液组织培养中发现了与疱疹病毒相符的包涵体，但无法从任何样本中直接培养出感染性病毒。数据表明，2型疱疹病毒在患有复发性生殖器感染的男性受试者精液中并非普遍存在。文中讨论了精液抑制剂和缺陷病毒在导致观察结果中可能发挥的作用，以及目前关于2型疱疹病毒传播的理论。
