Brandt D
Sonderkrankenanstalt für Herz-Kreislauf-Erkrankungen St. Radegund.
Wien Med Wochenschr. 1993;143(19-20):510-3.
Calcium antagonists reduce the peripheral vascular resistance thus lowering an elevated blood pressure. Due to their properties they are regarded as basic antihypertensiva. They do not affect metabolism, cause a regression of left ventricular hypertrophy and improve the vascular compliance. Serious side effects are extremely rare. Because of their effects they are especially suitable for the therapy of arterial hypertension with certain attendant and resultant diseases of high blood pressure and with the existence of certain demographic factors like age and race.
钙拮抗剂可降低外周血管阻力,从而降低升高的血压。因其特性,它们被视为基础降压药。它们不影响代谢,可使左心室肥厚消退并改善血管顺应性。严重副作用极为罕见。由于其作用,它们特别适用于治疗伴有某些高血压相关及由此引发疾病的动脉高血压,以及存在年龄和种族等特定人口统计学因素的情况。