Lechner W
Universitätsklinik für Frauenheilkunde, Innsbruck.
Wien Med Wochenschr. 1993;143(19-20):519-21.
In pregnancy calcium antagonism is of great importance. The uterus-relaxing properties of verapamil are well known, diltiazem shows an excellent tokolytic efficacy and is also effective as hypotensive in pregnancy-induced hypotension. In contrast to verapamil and diltiazem the dihydropyridines were not clinically successful as tokolytic or hypotensive in pregnancy. Magnesium is a therapy of first choice in the EPH-gestosis.
在孕期,钙拮抗作用非常重要。维拉帕米的子宫舒张特性是众所周知的,地尔硫䓬显示出优异的抑制宫缩功效,并且在妊娠诱发的低血压中作为降压药也有效。与维拉帕米和地尔硫䓬不同,二氢吡啶类药物在孕期作为宫缩抑制剂或降压药在临床上并不成功。镁是妊娠高血压综合征治疗的首选药物。