Viart P
Am J Clin Nutr. 1976 Jan;29(1):25-37. doi: 10.1093/ajcn/29.1.25.
The intravascular volumes were determined in 42 protein-calorie-depleted Shi children, and in 14 healthy patients. The red cell volume (RCV) was determined by a radiochromium technique; the total blood volume (TBV), the plasma volume (PV), and the total circulating albumin (TCA) were derived. The values were related to weight without edema, to expected weight for height, and to body surface area. Related values were averaged and were correlated with both the weight deviation and the plasma albumin level. Figures for healthy Shi children were comparable with American normal standards. Malnourished children were hypovolemic relative to their body size measurements; low TBV was the consequence of an absolute decrease in RCV and of a possible reduction of PV; TCA was lowered in the same proportion as albuminemia. RCV and TBV correlated well with albuminemia, but did not correlate with the weight deviation; the relationship between PV and albuminemia was not linear. Despite some quantitative discrepancies, similar results were obtained with each kind of related values. In a discussion of the results, stress is laid on risks of misinterpretation resulting from the use of anthropometric parameters as a basis of reference when studying intravascular volumes in marasmic kwashiorkor.
对42名蛋白质 - 热量缺乏的施氏儿童和14名健康患者测定了血管内容量。采用放射性铬技术测定红细胞容量（RCV）；由此得出总血容量（TBV）、血浆容量（PV）和总循环白蛋白（TCA）。这些数值与无水肿时的体重、身高预期体重以及体表面积相关。相关数值进行平均，并与体重偏差和血浆白蛋白水平相关联。施氏健康儿童的数据与美国正常标准相当。相对于其身体尺寸测量值，营养不良儿童血容量不足；低TBV是RCV绝对减少以及PV可能降低的结果；TCA与低白蛋白血症以相同比例降低。RCV和TBV与低白蛋白血症相关性良好，但与体重偏差无关；PV与低白蛋白血症之间的关系不是线性的。尽管存在一些数量上的差异，但每种相关数值都得到了类似的结果。在对结果的讨论中，强调了在研究消瘦型夸希奥科病的血管内容量时，以人体测量参数作为参考依据可能导致错误解读的风险。
