Liu H, Zhou J F
2nd Hospital of Zheijiang Medical University, Hanzhou.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 1993 Dec;13(12):714-7, 707.
80 patients of presenium hypertension with geriatric Kidney Qi Deficiency and Blood Stasis were randomly divided into two groups. (1) Traditional Chinese Medicine group (TCMG, 50 cases) treated with Xianbai Buyang Huanwu Decoction (XBH); (2) Western medicine group (WMG, 30 cases) treated with compound hypotensor tablets and gamma-evening primrose-E oil capsules.
The difference between the two groups was not significant (P > 0.05). After treatment, in TCMG, serum cholesterol and triglyceride, fibrinogen, whole blood viscosity and plasma viscosity, plasma and erythrocyte LPO activity lowered significantly, and plasma SOD and erythrocyte SOD raised significantly (P < 0.001-0.05), while in WMG, only showed the plasma LPO dropped (P < 0.05). The results suggested that XBH has the effects of reducing blood pressure, lowering the blood lipid, improving hemorrheological parameters and antioxidation.
80例老年前期高血压兼老年肾气虚血瘀患者被随机分为两组。（1）中药组（50例），采用仙白补阳还五汤（XBH）治疗；（2）西药组（30例），采用复方降压片和γ-月见草油胶囊治疗。
两组间差异无统计学意义（P>0.05）。治疗后，中药组血清胆固醇、甘油三酯、纤维蛋白原、全血黏度和血浆黏度、血浆及红细胞LPO活性显著降低，血浆SOD和红细胞SOD显著升高（P<0.001 - 0.05），而西药组仅血浆LPO下降（P<0.05）。结果提示，仙白补阳还五汤具有降压、降脂、改善血液流变学参数及抗氧化作用。
