Wang R
Beijing Medical University.
Zhonghua Liu Xing Bing Xue Za Zhi. 1993 Oct;14(5):295-9.
On the basis of understanding multistage pattern of the development of gastric cancer, we designed and carried out a new case-control study. The methods of analysis was multigroup logistic regression analysis. The studied objects were 4 groups of cases and 1 group of control. They were gastric Cancer group, severe dysplasia group, chronic atrophic gastritis accompanied by intestinal metaplasia group, ulcer group and control group, respectively. The control group was confirmed by pathology which showed that the gastric mucosa was normal or had only mild chronic superficial gastritis. The results showed that the risk factors of gastric cancer were living in high incidence area for a long period, low economic income, low animal protein intake, high sweet potato and inkfish intake, eating and drinking too much at one meal and mental injuring. The risk factors of severe dysplasia were low intake of protein, intake of non-fresh fish, large intake of inkfish and salted meat, a family history of gastric cancer.
在了解胃癌发生发展的多阶段模式的基础上，我们设计并开展了一项新的病例对照研究。分析方法为多组逻辑回归分析。研究对象为4组病例和1组对照。它们分别是胃癌组、重度发育异常组、伴有肠化生的慢性萎缩性胃炎组、溃疡组和对照组。对照组经病理证实胃黏膜正常或仅有轻度慢性浅表性胃炎。结果显示，胃癌的危险因素为长期居住在高发地区、经济收入低、动物蛋白摄入量低、红薯和墨鱼摄入量高、暴饮暴食和精神创伤。重度发育异常的危险因素为蛋白质摄入量低、食用不新鲜鱼类、大量摄入墨鱼和腌肉、有胃癌家族史。
