Fei Su Juan, Xiao Shu Dong
Shanghai Institute of Digestive Disease, Renji Hospital, Shanghai Jiaotong University, Shanghai, China.
Chin J Dig Dis. 2006;7(2):83-8. doi: 10.1111/j.1443-9573.2006.00252.x.
The incidence rates of gastric cancer in Shanghai urban districts have been markedly declining over the past three decades. From 1972 to 2001 the age-adjusted incidence rates of gastric cancer decreased from 62.0 to 32.5 per 100,000 in men and from 23.9 to 16.9 per 100,000 in women. This study aimed to investigate the relationship between environmental factors, in particular dietary factors, and the development of gastric cancer in those who lived in Shanghai urban districts for more than 15 years, and to explore the causes that led to the reduction of the incidence rates of gastric cancer in Shanghai.
One hundred and eighty-nine patients with gastric cancer and 567 age and sex-matched controls were surveyed with a questionnaire. SPSS software package was used to perform the univariate and multivariate unconditional logistic regression analysis modeling.
Vitamin supplements, use of home refrigerators, high consumption of fresh fruits and vegetables, bean and dairy products, and good meal habits were protective factors against gastric cancer. However, family history of cancer, chronic gastric diseases, increased intake of salted, pickled, fried and smoked foods, poor meal habits, smoking and alcohol drinking were risk factors for gastric cancer.
The reduction of the incidence of gastric cancer in Shanghai urban district in the past three decades is closely related to environmental factors, in particular dietary factors and wide use of home refrigerators.
在过去三十年中，上海市区胃癌发病率显著下降。1972年至2001年，男性胃癌年龄调整发病率从每10万人62.0例降至32.5例，女性从每10万人23.9例降至16.9例。本研究旨在调查环境因素，尤其是饮食因素，与在上海市区居住超过15年人群胃癌发生之间的关系，并探究导致上海胃癌发病率下降的原因。
采用问卷调查189例胃癌患者和567例年龄、性别匹配的对照。使用SPSS软件包进行单因素和多因素非条件logistic回归分析建模。
补充维生素、使用家用冰箱、大量食用新鲜水果和蔬菜、豆类及奶制品以及良好的饮食习惯是胃癌的保护因素。然而，癌症家族史、慢性胃病、咸腌、油炸和烟熏食品摄入量增加、不良饮食习惯、吸烟和饮酒是胃癌的危险因素。
过去三十年上海市区胃癌发病率的下降与环境因素密切相关，尤其是饮食因素和家用冰箱的广泛使用。
