Xiao J Z, Li G W, Pan X R
China-Japan Friendship Hospital, Beijing.
Zhonghua Nei Ke Za Zhi. 1993 Nov;32(11):760-2.
We analysed the data of 395 nondiabetic obese (BMI 25-42.2, impaired glucose tolerance, IGT, 257 and normal glucose tolerance, NGT, 138) and 482 nonobese subjects (BMI 15.9-24.9, IGT 170 and NGT 312). The blood pressure, plasma glucose, insulin, triglyceride and total cholesterol in obese were higher than that in nonobese, while HDL-c level was lower after controlling for age and sex (P < 0.001). This difference remained to be significant even after the adjustment of age, sex, insulin and 2-hours plasma glucose. Therefore, it was suggested that obesity was easy of access to coronary heart disease risk factors independent of hyperglycemia and hyperinsulinemia.
我们分析了395名非糖尿病肥胖者（体重指数[BMI]为25 - 42.2，糖耐量受损[IGT]者257名，糖耐量正常[NGT]者138名）和482名非肥胖者（BMI为15.9 - 24.9，IGT者170名，NGT者312名）的数据。在控制年龄和性别后，肥胖者的血压、血糖、胰岛素、甘油三酯和总胆固醇高于非肥胖者，而高密度脂蛋白胆固醇（HDL - c）水平较低（P < 0.001）。即使在调整年龄、性别、胰岛素和2小时血糖后，这种差异仍然显著。因此，提示肥胖易于获得独立于高血糖和高胰岛素血症的冠心病危险因素。
