唾液放射免疫分析法测定黄体期孕酮的参考值。

Reference values for luteal progesterone measured by salivary radioimmunoassay.

作者信息

Lipson S F, Ellison P T

机构信息

Department of Anthropology, Harvard University, Cambridge, Massachusetts 02138.

出版信息

Fertil Steril. 1994 Mar;61(3):448-54. doi: 10.1016/s0015-0282(16)56574-1.

DOI:10.1016/s0015-0282(16)56574-1

PMID:8137965

Abstract

OBJECTIVE

To establish age-stratified reference values for salivary luteal P levels.

DESIGN

One hundred thirty-six regularly menstruating women (18 to 48 years of age), screened for weight, exercise, and steroid medication use, collected daily saliva samples for one complete menstrual cycle. Luteal P levels were measured by 3H-RIA, and data were aligned by day of next menstrual onset. Means (+/- 1 SD range) and percentiles, calculated using both untransformed and log transformed data, were calculated for each luteal day and for indices of luteal P production.

RESULTS

Reference values for salivary daily luteal P levels and indices of luteal P are presented for three age groups (18 to 24 years, 25 to 39 years, and 40 to 48 years).

CONCLUSION

The age-stratified reference values presented here can be used, without collateral clinical procedures, to assess salivary luteal P levels. Salivary monitoring is ideally suited for research and long-term clinical observation, but the characteristics of salivary P data may limit the usefulness of these values for individual diagnosis.

摘要

目的

建立唾液黄体期孕酮水平的年龄分层参考值。

设计

136名规律月经的女性（18至48岁），对体重、运动和类固醇药物使用情况进行筛查，在一个完整的月经周期内每日采集唾液样本。采用3H放射免疫分析法测定黄体期孕酮水平，并根据下次月经来潮日期对齐数据。计算每个黄体期以及黄体期孕酮产生指标的均值（±1标准差范围）和百分位数，数据计算分别使用未转换数据和对数转换数据。