Walker S M, Walker R F, Riad-Fahmy D
Horm Res. 1984;20(4):231-40. doi: 10.1159/000180002.
A 'normal range' for salivary progesterone concentrations has been established using data derived from women who were menstruating regularly and in whom dating of the cycle by accepted criteria was possible. Since these values are in agreement with those in the first 9 days of conception cycles and with those in cycles in which ovulation was confirmed by ultrasonography, they provide a reliable index of progesterone output compatible with fertility. Measurement of daily salivary progesterone values in subfertile women for time spans exceeding 3 months allowed accurate assessment of base-line ovarian activity and of the response to ovulation-induction therapy. Salivary sampling, by allowing collection of frequent samples with a minimum of time, stress and inconvenience, is ideally suited to longitudinal studies of ovarian activity. This sampling regimen is also applicable to the monitoring of progesterone output throughout pregnancy.
通过收集月经周期规律且可依据公认标准确定周期时间的女性数据，已确立唾液孕酮浓度的“正常范围”。由于这些数值与受孕周期头9天以及经超声检查确认有排卵的周期中的数值相符，它们提供了一个与生育能力相符的可靠孕酮分泌指标。对不育女性超过3个月的时间段内每日唾液孕酮值进行测量，能够准确评估基线卵巢活动以及对促排卵治疗的反应。唾液采样能够在最短的时间、最小的压力和最少的不便情况下收集频繁的样本，非常适合对卵巢活动进行纵向研究。这种采样方案也适用于整个孕期孕酮分泌的监测。
