Gottschalk B, Richman R A, Lewandowski L
Psychology Department, Syracuse University, NY 13244.
Dev Med Child Neurol. 1994 Mar;36(3):216-20. doi: 10.1111/j.1469-8749.1994.tb11834.x.
This study surveyed the development and functioning of a group of 16 children with congenital hypothyroidism who had been followed closely since treatment was instituted at an average age of 15.6 days. This group of early-treated young children had no deficits in cognitive or adaptive functioning. Some isolated motor deficits were found, although results of the Finger-tapping and Marching subtests of the Reitan-Indiana battery did not replicate the New England Congenital Hypothyroid Collaborative (1985) finding of impaired performance. Speech deficits were documented in some. Congenitally hypothyroid children with delayed neonatal bone-age performed more poorly on most measures than those whose bone-age had been normal at birth.
本研究调查了一组16名先天性甲状腺功能减退症儿童的发育和功能情况，这些儿童自平均15.6日龄开始接受治疗后便一直受到密切跟踪。这组早期接受治疗的幼儿在认知或适应性功能方面没有缺陷。虽然瑞坦-印第安纳成套测验的手指敲击和行进分测验结果并未重现新英格兰先天性甲状腺功能减退协作组（1985年）所发现的表现受损情况，但仍发现了一些孤立的运动缺陷。部分儿童存在言语缺陷。新生儿骨龄延迟的先天性甲状腺功能减退儿童在大多数测量指标上的表现比出生时骨龄正常的儿童更差。
