Weller R E, Málaga C A, Buschbom R L, Ragan H A
Battelle Pacific NW Laboratories, Richland, WA 99352.
J Med Primatol. 1993 Aug;22(6):340-7.
The activity of three urinary enzymes, alkaline phosphatase (ALP), aspartate aminotransferase (AST), and N-acetyl-beta-D-glucosaminidase (NAG), was evaluated in 71 adult owl monkeys. Fifty-six animals had normal renal function, while 15 had evidence of renal dysfunction. Urinary enzyme: urinary creatinine ratios (UE: UCr) were also determined. The activity for NAG was similar to that of other species, while ALP and AST were higher. Regression analyses revealed that urinary enzymes and UE:UCr were significantly correlated (P < or = 0.0001) with indices of renal damage and could identify active renal disease.
对71只成年猫头鹰猴的三种尿酶（碱性磷酸酶（ALP）、天冬氨酸转氨酶（AST）和N-乙酰-β-D-氨基葡萄糖苷酶（NAG））活性进行了评估。56只动物肾功能正常，而15只动物有肾功能不全的证据。还测定了尿酶与尿肌酐比值（UE:UCr）。NAG的活性与其他物种相似，而ALP和AST的活性较高。回归分析显示，尿酶和UE:UCr与肾损伤指标显著相关（P≤0.0001），并可识别活动性肾脏疾病。
