海德果蝇Y染色体核糖体RNA基因数量的变异

Variations in the number of the Y chromosomal rRNA genes in Drosophila hydei.

作者信息

Kunz W

出版信息

Genetics. 1976 Jan;82(1):25-34. doi: 10.1093/genetics/82.1.25.

DOI:10.1093/genetics/82.1.25

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1213442/

Abstract

The number of rRNA cistrons is measured by filter saturation hybridization in different stocks of D. hydei, where the wild-type X chromosome has one nucleolus organizer (NO) and wild-type Y has two separated NO's. XX/Y females having no X chromosomal NO show an rDNA content exceeding that of a Y chromosome. An even greater increase in the rRNA cistron number is measured in two translocation stocks where the XX is combined with one half of a Y and, therefore, each stock contains only one of the two Y chromosomal NO's. But when the same Y fragments are brought together with a wild-type X chromosome they lose about one-half of their rRNA cistrons within one generation. Males with two complementary Y fragments but having no X chromosomal NO show a considerably higher rDNA content than the XX/Y females, although both are equal in respect of their NO number. Consideration is given to related phenomena in Drosophila melanogaster.

摘要

通过滤膜饱和杂交法测量了海德氏果蝇不同品系中核糖体RNA顺反子的数量，其中野生型X染色体有一个核仁组织区（NO），野生型Y染色体有两个分开的核仁组织区。没有X染色体核仁组织区的XX/Y雌性果蝇的核糖体DNA含量超过Y染色体。在两个易位品系中测量到核糖体RNA顺反子数量有更大幅度的增加，在这两个品系中XX与Y染色体的一半结合，因此每个品系只包含两个Y染色体核仁组织区中的一个。但是，当相同的Y片段与野生型X染色体结合时，它们在一代之内会失去大约一半的核糖体RNA顺反子。具有两个互补Y片段但没有X染色体核仁组织区的雄性果蝇的核糖体DNA含量比XX/Y雌性果蝇高得多，尽管两者的核仁组织区数量相同。文中还考虑了黑腹果蝇中的相关现象。

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