Keller W G, Aron D N, Rakich P M, Crowe D T, Marks M A
Department of Small Animal Medicine, College of Veterinary Medicine, University of Georgia.
Vet Surg. 1994 Jan-Feb;23(1):31-9. doi: 10.1111/j.1532-950x.1994.tb00439.x.
In phase I, tissue expanders were implanted subcutaneously over the lateral crural region of four dogs. The expanders were inflated daily to maintain a constant intraluminal pressure for 7 days. All animals tolerated the pressurized expanders well. Some animal patient discomfort was associated with repeated injections into the subcutaneous filling port. One dog developed a limited area of tissue loss and exposure of the expander. Tissue response to the expanders included epidermal hyperplasia, dermal collagen compression with early fibroplasia, and subcutaneous granulation tissue formation adjacent to the expander pocket. In phase II, a second group of four dogs underwent rapid skin expansion over 7 days. The pressure applied to the expanding skin was determined daily and adjusted to approximate the value reported for capillary pressure in the dog. Tissue discoloration occurred in two dogs, suggestive of impaired circulation. Skin flaps were developed from expanded skin and rotated over the talocrural region. Wound dehiscence occurred along the distal flap margin in three phase II dogs. These wounds healed by second intention. Branches of the caudal saphenous artery were identified, using angiography, as the primary blood supply to the skin flaps.
在第一阶段，将组织扩张器皮下植入四只狗的小腿外侧区域。每天对扩张器进行充气，以维持恒定的腔内压力，持续7天。所有动物对加压扩张器耐受良好。一些动物患者的不适与反复注射到皮下填充端口有关。一只狗出现了有限区域的组织损失和扩张器暴露。组织对扩张器的反应包括表皮增生、真皮胶原压缩伴早期纤维增生，以及扩张器腔隙邻近区域的皮下肉芽组织形成。在第二阶段，第二组四只狗在7天内进行了快速皮肤扩张。每天确定施加在扩张皮肤上的压力，并进行调整，使其接近报道的狗毛细血管压力值。两只狗出现了组织变色，提示循环受损。从扩张的皮肤形成皮瓣，并旋转至距小腿区域。在第二阶段的三只狗中，伤口在皮瓣远端边缘处裂开。这些伤口通过二期愈合。通过血管造影确定，隐后动脉分支是皮瓣的主要血液供应来源。
