Mishima K, Okawa M, Hishikawa Y, Hozumi S, Hori H, Takahashi K
Department of Neuropsychiatry, Akita University School of Medicine, Japan.
Acta Psychiatr Scand. 1994 Jan;89(1):1-7. doi: 10.1111/j.1600-0447.1994.tb01477.x.
Fourteen inpatients with dementia showing sleep and behavior disorders (average age = 75 years), and 10 control elderly people (average age = 75 years) were carefully observed for 2 months. Four weeks of morning light therapy markedly improved sleep and behavior disorders in the dementia group. The measurement of sleep time and the serum melatonin values suggests that sleep and behavior disorders in the dementia group are related to decreases in the amplitude of the sleep-wake rhythm and decreases in the levels of melatonin secretions. Morning light therapy significantly increased total and nocturnal sleep time and significantly decreased daytime sleep time. These results indicate that morning bright light is a powerful synchronizer that can normalize disturbed sleep and substantially reduce the frequency of behavior disorders in elderly people with dementia.
对14名患有睡眠和行为障碍的痴呆症住院患者（平均年龄 = 75岁）以及10名对照老年人（平均年龄 = 75岁）进行了为期2个月的仔细观察。为期四周的早晨光照疗法显著改善了痴呆症组的睡眠和行为障碍。睡眠时间和血清褪黑素值的测量表明，痴呆症组的睡眠和行为障碍与睡眠-觉醒节律的幅度降低以及褪黑素分泌水平降低有关。早晨光照疗法显著增加了总睡眠时间和夜间睡眠时间，并显著减少了白天睡眠时间。这些结果表明，早晨明亮的光线是一种强大的同步器，可以使紊乱的睡眠正常化，并大幅降低患有痴呆症的老年人行为障碍的发生率。
