Peter J C, Domingo Z, Sinclair-Smith C, de Villiers J C
Department of Neurosurgery and Pathology, Red Cross Children's Hospital, University of Cape Town, South Africa.
Pediatr Neurosurg. 1994;20(1):78-83. doi: 10.1159/000120769.
The radiological, surgical and pharmacological management of 11 children with cerebral hydatid disease is presented with special emphasis on the varying CT and MRI appearances and the surgical difficulties we have encountered. All but 2 had enhanced CT scanning and 2 had an MRI. The typical CT appearance of a large non-enhancing cyst of CSF density with minimal oedema was only seen in 3 children. Atypical appearances included irregularity of the cyst wall contour (2), enhancement of the surrounding rim (3), isodensity or heterogeneity of the cyst content (4), surrounding oedema (4) and globular as opposed to curvilinear calcification (2). Complete intact cyst removal was achieved in 3 patients. The reasons for puncturing the cysts or rupturing them at operation were failure to make a definitive pre-operative diagnosis (5), dense adhesions to the skull, dura or falx (3) and the misdiagnosis of an arachnoid cyst and the subsequent placement of a cystoperitoneal shunt (1). Pathological examination suggests that the degree of the inflammatory response to the ectocyst may determine the enhancement characteristics and the ease of surgical removal. There was 1 recurrence which responded well to four 28-day treatment cycles of albendazole.
本文介绍了11例脑包虫病患儿的放射学、外科及药物治疗情况,特别强调了不同的CT和MRI表现以及我们所遇到的手术困难。除2例患儿外,其余均接受了增强CT扫描,2例进行了MRI检查。仅3例患儿出现典型的CT表现,即脑脊液密度的大的无强化囊肿且水肿轻微。非典型表现包括囊肿壁轮廓不规则(2例)、周边边缘强化(3例)、囊肿内容物等密度或不均匀(4例)、周边水肿(4例)以及球形而非曲线形钙化(2例)。3例患者实现了完整囊肿切除。术中穿刺囊肿或使其破裂的原因包括术前未能做出明确诊断(5例)、与颅骨、硬脑膜或大脑镰紧密粘连(3例)以及蛛网膜囊肿误诊并随后放置囊肿-腹腔分流管(1例)。病理检查表明,对外囊的炎症反应程度可能决定强化特征及手术切除的难易程度。有1例复发,经四个28天的阿苯达唑治疗周期后反应良好。