异烟肼的分子机制：结核病控制一线用药
Molecular mechanisms of isoniazid: a drug at the front line of tuberculosis control.
作者信息
Zhang Y, Young D B
机构信息
MRC Tuberculosis and Related Infections Unit, RPMS, Hammersmith Hospital, London, UK.
出版信息
Trends Microbiol. 1993 Jun;1(3):109-13. doi: 10.1016/0966-842x(93)90117-a.
PMID:8143118
Abstract
The resurgence of tuberculosis and emergence of multidrug-resistant isolates has focused attention on the need for an improved understanding of molecular aspects of the disease, and for elucidation of the factors responsible for drug action and resistance. Recent research has probed the mechanism of action of isoniazid (INH), a key drug in the chemotherapy of tuberculosis.
摘要
结核病的再度流行以及多重耐药菌株的出现，使得人们将注意力集中在需要更好地理解该疾病的分子层面，以及阐明药物作用和耐药性的相关因素上。最近的研究探究了异烟肼（INH）的作用机制，异烟肼是结核病化疗中的一种关键药物。
Zotero 插件