Iwa N, Yutani C
Division of Pathology, National Sasayama Hospital, Hyogo, Japan.
Diagn Cytopathol. 1993 Dec;9(6):661-4. doi: 10.1002/dc.2840090611.
Cytological findings are presented of seven cases of cardiac myxomas. Avidin-biotin-peroxidase complex (ABC) method was employed to demonstrate Ulex europaeus agglutinin-I (UEA-I) lectin in imprint smears as well as in paraffin-embedded tissue sections in cardiac myxomas. The cytology was characterized by tumor cells with polyhedral or stellate and mucinous background with lymphocytes, neutrophils, and hemosiderin-laden macrophages. In smears as well as tissue sections, UEA-I lectin was detected throughout the cytoplasm of myxoma cells. This study established the applicability of the immunoperoxidase staining for cardiac myxoma as an aid in cytopathological diagnosis.
本文呈现了7例心脏黏液瘤的细胞学检查结果。采用抗生物素蛋白-生物素-过氧化物酶复合物（ABC）法，在心脏黏液瘤的印片涂片以及石蜡包埋组织切片中显示欧洲荆豆凝集素-I（UEA-I）凝集素。细胞学特征为肿瘤细胞呈多面体或星状，背景为黏液性，伴有淋巴细胞、中性粒细胞和含铁血黄素巨噬细胞。在涂片和组织切片中，均在黏液瘤细胞的整个细胞质中检测到UEA-I凝集素。本研究确立了免疫过氧化物酶染色在心脏黏液瘤细胞病理学诊断中的应用价值。
