Nakamura S, Koshikawa T, Kaba S, Tokoro Y, Suchi T, Kurita S
Department of Pathology and Clinical Laboratories, Aichi Cancer Center Hospital, Nagoya, Japan.
Diagn Cytopathol. 1993 Dec;9(6):665-7. doi: 10.1002/dc.2840090612.
Low-grade B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) arising in the thymus is a very rare tumor with characteristic morphologic features. We describe a case of thymic low-grade B-cell MALT lymphoma occurring in a 59-yr-old woman with Sjögren's syndrome, in whom the definite diagnosis was difficult at the time of surgery. An immunohistologic and genotypic study, however, was diagnostic of lymphoma. A review of cytologic material was undertaken, and it was felt that the cytologic features in Giemsa-stained preparations in imprint smears were present that initially should have enabled the correct cytodiagnosis and distinction from the other thymic lesions. The findings presented in this study were considered to contribute to the cytodiagnosis of a thymic lesion, which might, in the past, have been erroneously interpreted as another lymphoproliferative disorder.
起源于胸腺的黏膜相关淋巴组织（MALT）低度B细胞淋巴瘤是一种具有特征性形态学特征的非常罕见的肿瘤。我们描述了一例发生在一名59岁干燥综合征女性患者中的胸腺低度B细胞MALT淋巴瘤病例，该患者在手术时难以明确诊断。然而，免疫组织学和基因分型研究确诊为淋巴瘤。我们对细胞学材料进行了回顾，发现在印片涂片吉姆萨染色制剂中存在细胞学特征，这些特征最初应能实现正确的细胞诊断并与其他胸腺病变相鉴别。本研究中的发现被认为有助于胸腺病变的细胞诊断，过去这种病变可能被错误地解释为另一种淋巴增殖性疾病。
