Loidl J
Institute of Botany, University of Vienna, Austria.
Experientia. 1994 Mar 15;50(3):285-94. doi: 10.1007/BF01924012.
This article reviews current views on the mechanisms of meiotic homology searching and recombination. It discusses the relationship between molecular events at meiotic prophase and concomitant cytological processes. The role of the synaptonemal complex and other meiosis-specific structures is discussed. Whereas the relationship of crossovers, late recombination nodules, and chiasmata is well established, there is still some controversy about the temporal and causal relationships between double strand breaks, homologue recognition, heteroduplexes, early nodules and presynaptic alignment.
本文综述了当前关于减数分裂同源性搜索和重组机制的观点。它讨论了减数分裂前期的分子事件与伴随的细胞学过程之间的关系。还讨论了联会复合体和其他减数分裂特异性结构的作用。虽然交叉、后期重组结节和交叉的关系已经明确,但关于双链断裂、同源物识别、异源双链体、早期结节和突触前排列之间的时间和因果关系仍存在一些争议。