Brockerhoff P, Bahlmann F, Casper F, Seufert K
Frauenklinik, Universität Mainz.
Zentralbl Gynakol. 1994;116(2):64-7.
In a special analysis of the perinatal database Rheinl.-Pfalz of the years 1989 and 1990 1,876 pregnancies with the risk-factor "gestosis" (2.4% of all deliveries) were evaluated. In comparison to all deliveries (n = 78,250) significantly different incident-rates could be observed: Sterility, working during pregnancy, nationality, parity, psycho-social stress, multiples, adipositas, diabetes mellitus, pathological increase of body weight, urinary infection, number and duration of antenatal hospitalisation. Prematurity and fetal retardation as well as placental insufficiency, pathological antenatal CTG, green amniotic fluid and intrapartel acidosis was seen much more often in the risk group, resulting in a much higher rate of caesarean section (50.1 versus 13.7%) and an increased maternal and fetal morbidity. Perinatal mortality was twice as high in the risk group compared to the control. Thought data quality is limited in this study covering a very larger area, the results underline the unchanged importance of hypertensive disorders in perinatology.
在一项对1989年和1990年莱茵兰-普法尔茨州围产期数据库的专项分析中,对1876例存在“妊娠中毒症”风险因素的妊娠病例(占所有分娩病例的2.4%)进行了评估。与所有分娩病例(n = 78,250)相比,可以观察到显著不同的发病率:不育、孕期工作、国籍、产次、心理社会压力、多胎妊娠、肥胖症、糖尿病、体重病理性增加、泌尿系统感染、产前住院次数和时长。早产、胎儿发育迟缓以及胎盘功能不全、病理性产前胎心监护、羊水粪染和产时酸中毒在风险组中更为常见,导致剖宫产率显著更高(50.1%对13.7%),母婴发病率增加。与对照组相比,风险组的围产期死亡率高出一倍。尽管这项覆盖范围非常大的研究数据质量有限,但结果强调了高血压疾病在围产医学中仍然具有重要意义。