Pansini F, Campobasso C, Giorgetti L, Locorotondo G C, Agnello G, Bassi P, Costantino D, Sighinolfi D, Alvisi V, Mollica G
Department of Obstetrics and Gynecology, University of Ferrara, Italy.
Gynecol Endocrinol. 1993 Dec;7(4):267-71. doi: 10.3109/09513599309152511.
A total of 615 healthy fertile women (518 pill users and 97 non-users) were examined by real-time ultrasonography for fasting gallbladder volume, gallstones and biliary dysmorphism. None of the six examined combinations of oral contraceptives appeared to influence fasting gallbladder volume significantly. When fasting gallbladder volumes were reanalyzed according to the presence or absence of recognized biliary risk factors, significant modifications were detected, in both pill users and non-users. These changes related only to age and parity. Relative risks of cholelithiasis and biliary dysmorphism were not affected by contraceptive treatment.
共有615名健康可育女性（518名口服避孕药使用者和97名非使用者）接受了实时超声检查，以测量空腹胆囊容积、胆结石和胆囊形态异常情况。六种口服避孕药的组合均未显示出对空腹胆囊容积有显著影响。当根据是否存在公认的胆道危险因素重新分析空腹胆囊容积时，在口服避孕药使用者和非使用者中均检测到了显著变化。这些变化仅与年龄和产次有关。避孕药治疗对胆结石和胆囊形态异常的相对风险没有影响。
