Zorlu C G, Aral K, Cobanoglu O, Gürler S, Gokmen O
Family Planning Clinic, Dr Zekai Tahir Burak Women's Hospital, Ankara, Turkey.
Adv Contracept. 1993 Dec;9(4):299-302. doi: 10.1007/BF01983207.
In the present study, we tried to determine whether IUD insertion related PID and febrile complications could be prevented by prophylactic use of antibiotics. We studied 300 patients who were admitted to our family planning clinic for IUD contraception. Of these, 150 patients received prophylactic Doxycycline (group 1) and the second 150 received no therapy (group 2). Five cases experienced fever with or without leucocytosis and none required hospitalization. PID was observed in one woman in each group. Positive culture (gonorrhea) was obtained in one woman who was then treated by relevant antibiotics; the other woman required hospitalization for two days. The overall infection rates for group 1 and 2 were 2.1% and 2.9%, respectively and this difference was not significant. The incidence of PID infection and febrile complications was found to be very low for both groups when compared to other studies, suggesting that aseptic conditions with proper insertion reduce the risk of infection.
在本研究中，我们试图确定预防性使用抗生素是否可以预防与宫内节育器（IUD）插入相关的盆腔炎（PID）和发热并发症。我们研究了300名因IUD避孕而入住我们计划生育诊所的患者。其中，150名患者接受了预防性强力霉素治疗（第1组），另外150名患者未接受治疗（第2组）。5例患者出现发热，伴或不伴有白细胞增多，均无需住院治疗。每组各有1名女性被观察到患有PID。1名女性培养结果呈阳性（淋病），随后接受了相关抗生素治疗；另1名女性需要住院两天。第1组和第2组的总体感染率分别为2.1%和2.9%，差异不显著。与其他研究相比，两组的PID感染和发热并发症发生率都非常低，这表明在无菌条件下正确插入IUD可降低感染风险。
