Russell M E, Weiss K M, Buchanan A V, Etherton T D, Moore J H, Kris-Etherton P M
Nutrition Department, Pennsylvania State University, University Park 16802.
Am J Clin Nutr. 1994 Apr;59(4):847-52. doi: 10.1093/ajcn/59.4.847.
Plasma lipids, lipoproteins, and apolipoproteins were measured in 123 female and 57 male Mvskoke Indians, a population of American Indians with a high prevalence of non-insulin-dependent diabetes mellitus (NIDDM). Dietary patterns were assessed with a food-frequency questionnaire. There were no differences in total cholesterol, low-density-lipoprotein cholesterol (LDL-C), high-density-lipoprotein cholesterol (HDL-C), apolipoproteins A-I or B in female Indians with and without diabetes. In males with diabetes, however, LDL-C was lower. Triglyceride and fasting plasma glucose were higher in subjects with diabetes. Total cholesterol and LDL-C were lower and HDL-C was higher than age and sex-matched Lipid Research Clinics values, especially for subjects with diabetes. This is surprising given that the diet of Mvskoke Indians contains foods high in total fat, saturated fatty acids, and cholesterol. We may explain, in part, the low incidence of coronary heart disease in this population.
在123名女性和57名男性马斯柯基印第安人（Mvskoke Indians）中测量了血浆脂质、脂蛋白和载脂蛋白，这是一个非胰岛素依赖型糖尿病（NIDDM）患病率很高的美洲印第安人群体。通过食物频率问卷评估饮食模式。患有糖尿病和未患糖尿病的女性印第安人在总胆固醇、低密度脂蛋白胆固醇（LDL-C）、高密度脂蛋白胆固醇（HDL-C）、载脂蛋白A-I或B方面没有差异。然而，患有糖尿病的男性中，LDL-C较低。糖尿病患者的甘油三酯和空腹血糖较高。总胆固醇和LDL-C低于年龄和性别匹配的脂质研究诊所的值，而HDL-C高于该值，尤其是糖尿病患者。鉴于马斯柯基印第安人的饮食中含有高脂肪、饱和脂肪酸和胆固醇的食物，这一结果令人惊讶。我们可以部分解释该人群冠心病发病率低的原因。
