人类免疫缺陷病毒（HIV）和获得性免疫缺陷综合征（AIDS）中的情绪及精神障碍：随时间的变化

Mood and psychiatric disturbance in HIV and AIDS: changes over time.

作者信息

Fell M, Newman S, Herns M, Durrance P, Manji H, Connolly S, McAllister R, Weller I, Harrison M

机构信息

Department of Academic Psychiatry, University College and Middlesex School of Medicine, Middlesex Hospital, London.

出版信息

Br J Psychiatry. 1993 May;162:604-10. doi: 10.1192/bjp.162.5.604.

DOI:10.1192/bjp.162.5.604

PMID:8149111

Abstract

A sample of 26 HIV seronegative, 59 HIV seropositive asymptomatic and 7 HIV seropositive symptomatic homosexual and bisexual men were assessed over two visits, a mean of 11 months apart, using the BDI, STAI, and CIS. Significant differences emerged between the symptomatic group and the other two groups. Past psychiatric history and the somatic items in the assessments accounted for some of these differences. The seropositive asymptomatic and the seronegative groups did not differ on any of the mood or psychiatric assessments, suggesting minimal effect on psychological well-being of seroconversion in the absence of symptoms.

摘要

对26名HIV血清学阴性、59名无症状HIV血清学阳性以及7名有症状的HIV血清学阳性的男同性恋者和双性恋男性进行了两次评估，两次评估间隔平均为11个月，评估采用贝克抑郁量表（BDI）、状态特质焦虑量表（STAI）和临床印象量表（CIS）。有症状组与其他两组之间出现了显著差异。既往精神病史以及评估中的躯体项目在一定程度上解释了这些差异。无症状血清学阳性组和血清学阴性组在任何情绪或精神评估方面均无差异，这表明在无症状的情况下，血清转化对心理健康的影响极小。