未接受过抗精神病药物治疗的精神分裂症患者的血小板单胺氧化酶活性：长期使用奋乃静治疗无影响。
Platelet monoamine oxidase activity in neuroleptic-naive schizophrenic patients: lack of influence of chronic perphenazine treatment.
作者信息
Spivak B, Kosower N, Zipser Y, Shreiber-Schul N, Apter A, Tyano S, Weizman A
机构信息
Gehah Psychiatric Hospital, Petah Tiqva, Israel.
出版信息
Clin Neuropharmacol. 1994 Feb;17(1):83-8.
PMID:8149362
Abstract
We investigated the possible relationship between schizophrenia, neuroleptic treatment, and platelet monoamine oxidase (MAO) activity. Platelet MAO activity was similar in neuroleptic-naive schizophrenic patients and healthy controls and was not affected by chronic (10-week) perphenazine treatment. A relationship between platelet MAO activity and central disturbances in schizophrenia remains uncertain.
摘要
我们研究了精神分裂症、抗精神病药物治疗与血小板单胺氧化酶（MAO）活性之间可能存在的关系。未接受过抗精神病药物治疗的精神分裂症患者与健康对照者的血小板MAO活性相似，且不受慢性（10周）奋乃静治疗的影响。血小板MAO活性与精神分裂症中枢功能紊乱之间的关系仍不明确。
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