Sacquet M E, Méjean C, Leprince C, Riottot M M
C R Acad Hebd Seances Acad Sci D. 1975 Nov 3;281(18):1337-9.
Comparative studies between groups of rats which differ by the microbial flora of their gastrointestinal tract, the weight of their caecum and the diet on which they are fed allow the following conclusions: 1. Caecal enlargement is, on the one hand, mainly responsible for the increased intestinal pool of bile salts in the intestine of germ-free rats and on the other has little action on the decrease of their fecal excretion. 2. Other than for intestinal flora, diet modifies intestinal pool and fecal excretion of bile salts. Fecal excretion mainly depends on diet cholesterol content. Intestinal pool size mainly depends on dietary factors which are different from cholesterol.
对胃肠道微生物菌群、盲肠重量及所喂食饮食不同的大鼠组进行比较研究,可得出以下结论:1. 一方面,盲肠增大是无菌大鼠肠道中胆汁盐肠池增加的主要原因,另一方面,对其粪便排泄减少作用不大。2. 除肠道菌群外,饮食会改变胆汁盐的肠池和粪便排泄。粪便排泄主要取决于饮食中的胆固醇含量。肠池大小主要取决于与胆固醇不同的饮食因素。