Pienkowski D, Pollack S R, Brighton C T, Griffith N J
University of Pennsylvania, Philadelphia 19104.
J Bone Joint Surg Am. 1994 Apr;76(4):489-501. doi: 10.2106/00004623-199404000-00003.
The purpose of this study was to determine whether low-power-consuming symmetrical-waveform electromagnetic stimuli could increase the stiffness of fracture sites in a rabbit fibular-osteotomy model. Both active and placebo devices were used in a blinded study protocol. Dose-response studies of pulse amplitude and pulse width were performed by continuous application (twenty-four hours a day) of repetitive (fifteen-hertz), bursted (five-millisecond-long) symmetrical, rectangular electromagnetic stimulus waveforms. The power consumed by these stimuli is approximately one-fifth that consumed by the pulsing electromagnetic field devices that are in current clinical use. Significant increase of callus bending stiffness was produced by pulse widths of five to seven microseconds and pulse amplitudes of fifty to 100 millivolts.
本研究的目的是确定低功耗对称波形电磁刺激能否在兔腓骨截骨模型中增加骨折部位的硬度。在一项盲法研究方案中使用了有源装置和安慰剂装置。通过每天持续（24小时）施加重复（15赫兹）、脉冲串（5毫秒长）的对称矩形电磁刺激波形，进行了脉冲幅度和脉冲宽度的剂量反应研究。这些刺激所消耗的功率约为目前临床使用的脉冲电磁场装置所消耗功率的五分之一。5至7微秒的脉冲宽度和50至100毫伏的脉冲幅度可使骨痂弯曲硬度显著增加。
