Siccardi A G, Ferrari F A, Mazza G, Galizzi A
J Bacteriol. 1976 Mar;125(3):755-61. doi: 10.1128/jb.125.3.755-761.1976.
The simultaneous replication of four regions of dichotomously replicating chromosomes of Bacillus subtilis has been detected by means of nitrosoguanidine-induced comutation. The map distance between successive rounds of replication has been measured as one-half a replicative arm in cells growing exponentially in rich medium.
通过亚硝基胍诱导的共突变,已检测到枯草芽孢杆菌二分体复制染色体四个区域的同时复制。在富含培养基中指数生长的细胞中,连续两轮复制之间的图谱距离经测定为一个复制臂的一半。