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白血病中的感染性肝病灶:短反转时间反转恢复序列、T1加权自旋回波序列及动态钆增强磁共振成像的比较

Infectious liver foci in leukemia: comparison of short-inversion-time inversion-recovery, T1-weighted spin-echo, and dynamic gadolinium-enhanced MR imaging.

作者信息

Lamminen A E, Anttila V J, Bondestam S, Ruutu T, Ruutu P J

机构信息

Department of Radiology, Helsinki University Hospital, Finland.

出版信息

Radiology. 1994 May;191(2):539-43. doi: 10.1148/radiology.191.2.8153336.

DOI:10.1148/radiology.191.2.8153336
PMID:8153336
Abstract

PURPOSE

To assess the performances of three different magnetic resonance (MR) imaging techniques in the evaluation of patients with leukemia and suspected hepatic candidiasis.

MATERIALS AND METHODS

Twelve patients with acute leukemia and definite or clinically suspected hepatic candidiasis were imaged at 1.0 T with a T1-weighted spin-echo (SE) technique, a short-inversion-time inversion-recovery (STIR) fat-suppression technique, and a dynamic gadolinium-enhanced fast low-angle shot (FLASH) technique. The conspicuity of hepatic lesions was evaluated semiquantitatively and ranked on a three-point scale.

RESULTS

Multiple liver lesions were seen as high-signal-intensity foci with the STIR sequence; other sequences showed equivocal results. In the semiquantitative evaluation, STIR was significantly (P < .001) superior to both T1-weighted SE and contrast-enhanced FLASH techniques. Multiple red blood cell transfusions affected lesion conspicuity.

CONCLUSION

STIR imaging is recommended as the MR technique of choice at 1.0 T in the evaluation of infectious liver foci in patients with acute leukemia.

摘要

目的

评估三种不同的磁共振(MR)成像技术在白血病合并疑似肝念珠菌病患者评估中的表现。

材料与方法

12例急性白血病合并明确或临床疑似肝念珠菌病的患者在1.0 T磁场下采用T1加权自旋回波(SE)技术、短反转时间反转恢复(STIR)脂肪抑制技术和动态钆增强快速低角度激发(FLASH)技术进行成像。对肝脏病变的显影情况进行半定量评估,并按三分制进行分级。

结果

STIR序列显示多个肝脏病变为高信号灶;其他序列结果不明确。在半定量评估中,STIR明显(P <.001)优于T1加权SE和对比增强FLASH技术。多次红细胞输血影响病变显影。

结论

对于急性白血病患者感染性肝病灶的评估,推荐在1.0 T时选用STIR成像作为MR技术。

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引用本文的文献

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Guidelines for the investigation of invasive fungal infections in haematological malignancy and solid organ transplantation. British Society for Medical Mycology.血液系统恶性肿瘤和实体器官移植中侵袭性真菌感染的调查指南。英国医学真菌学会。
Eur J Clin Microbiol Infect Dis. 1997 Jun;16(6):424-36. doi: 10.1007/BF02471906.
2
Pyogenic hepatic abscess. Changing trends over 42 years.化脓性肝脓肿。42年的变化趋势。
Ann Surg. 1996 May;223(5):600-7; discussion 607-9. doi: 10.1097/00000658-199605000-00016.