Mas J L
Service de neurologie, Centre Raymond Garcin, hôpital Sainte-Anne, Paris.
Rev Prat. 1993 Dec 1;43(19):2509-14.
Arterial dissection results from bleeding into the vessel wall. Some cases are associated with cervical trauma or have evidence of an underlying vascular disease; many occur without any history of injury or detectable arterial disease. Among the cervical cephalic arteries, the extracranial segment of the internal carotid artery is the vessel most commonly involved; intracranial carotid dissections are much rare. Carotid dissection occurs predominantly in young or middle-aged adults and shows no sex predominance. Although clinical manifestations can be extremely diverse (from isolated headache to rapidly lethal stroke), the most common and suggestive syndrome associates "local" symptoms (such as head or neck pain, Horner's syndrome, pulsatile tinnitus or lower cranial nerves palsy) and delayed (up to several weeks) symptoms of cerebral ischaemia in the territory of the internal carotid artery territory. Dissection can be bilateral or associated with dissection of the vertebral artery. Angiography has long been considered the gold standard for the diagnosis. As this procedure carries a risk of cerebral complications, noninvasive diagnostic approaches such as magnetic resonance imaging and ultrasound have been developed and are increasingly used. The prognosis of carotid dissections depends on the presence and severity of ischaemic brain damage. Recurrent dissections seem extremely rare. Normalization or improvement of the vascular abnormalities during the subsequent weeks is frequent and is an excellent argument in favour of the diagnosis. Although no controlled trial has ever been performed, anticoagulant treatment is often used for a few months when the dissection involves the extracranial segment of the carotid artery. No standard treatment of intracranial carotid dissection has emerged.
动脉夹层是由于血液渗入血管壁所致。部分病例与颈部创伤有关或有潜在血管疾病的证据;许多病例发生时没有任何损伤史或可检测到的动脉疾病。在颈内动脉中,颈外段是最常受累的血管;颅内段夹层则极为罕见。颈动脉夹层主要发生在中青年,无性别差异。尽管临床表现极为多样(从单纯头痛到迅速致死性中风),但最常见且具有提示性的综合征是将“局部”症状(如头部或颈部疼痛、霍纳综合征、搏动性耳鸣或低位颅神经麻痹)与颈内动脉供血区延迟(长达数周)出现的脑缺血症状相结合。夹层可为双侧性或与椎动脉夹层相关。长期以来,血管造影一直被视为诊断的金标准。由于该检查存在脑部并发症的风险,已开发出磁共振成像和超声等无创诊断方法并越来越多地被使用。颈动脉夹层的预后取决于缺血性脑损伤的存在及严重程度。复发性夹层似乎极为罕见。在随后几周内血管异常恢复正常或改善很常见,这有力地支持了诊断。尽管从未进行过对照试验,但当夹层累及颈动脉颈外段时,抗凝治疗通常会使用数月。目前尚未出现颅内段颈动脉夹层的标准治疗方法。