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[睡眠障碍的药物治疗]

[Pharmacotherapy of sleep disorders].

作者信息

Borbély A A

机构信息

Pharmakologisches Institut der Universität Zürich.

出版信息

Ther Umsch. 1993 Oct;50(10):709-12.

PMID:8153909
Abstract

Benzodiazepines and related drugs are the hypnotics of first choice. They shorten sleep latency, enhance sleep continuity and may prolong sleep duration. Their undesired effects include a persistent day-time sedation and ataxia when getting up at night. There is some risk of habit formation and dependence. For treating an acute insomnia, the prescription of hypnotics should be limited to a short duration (smallest package size), for treating chronic forms of insomnia they should have only an adjuvant role in therapy.

摘要

苯二氮䓬类药物及相关药物是首选的催眠药。它们可缩短入睡潜伏期,增强睡眠连续性,并可能延长睡眠时间。其不良反应包括持续的日间镇静作用以及夜间起床时的共济失调。存在一定的成瘾和依赖风险。治疗急性失眠时,催眠药的处方应限于短疗程(最小包装规格),治疗慢性失眠时,它们在治疗中应仅起辅助作用。

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