Bromirska D
Kliniki Ginekologii Instytutu Połoznictwa i Ginekologii Pomorskiej Akademii Medycznej.
Ann Acad Med Stetin. 1993;39:133-46.
The aim of the paper has been to study the effect of a single procedure with hyper (42 degrees C) and isothermic (37 degrees C) mud exerted on the hormonal function of normal and insufficient corpus luteum in women. Procedure with mud was the first of its kind sanatorium treatment and consisted in simultaneous use of wrapping and vaginal pack. That was performed in the compartment from 18 to 22-nd day of menstrual cycle in 55 women with normal function of corpus luteum. The number included 32 with hyper, and 23 with isothermic mud. In a group of 41 studied women with insufficient corpus luteum, in 21 hyper and in 20 isothermic mud was used. In all the women prior to the procedure, 2 and 5 hours after the procedure, the accomplished radioimmunological determinations involved: concentration of FSH, LH, progesterone and estradiol in blood serum. Moreover, the level of adrenaline and noradrenaline in urine was established by fluorimetric method, calculated for gram of creatinine. In 10 of them concentration of FSH and LH was being determined every 15 minutes for the first 2 hours following the procedure. The employed procedure with hyper or isothermic mud in a similar manner led to transient increase in the concentration of progesterone and estradiol in blood sera of women with normal and insufficient hormonal function of corpus luteum. There was also a significant rise in excretion of adrenaline and noradrenaline in urine, particularly after hyperthermic mud application. The mentioned increase in the concentration of steroids was disconnected with the elevation affecting the concentration of gonadotropins, but likely due to their discharge from ovaries.
本文旨在研究单次使用高温（42摄氏度）和等温（37摄氏度）泥浆疗法对女性正常和功能不全黄体激素功能的影响。泥浆疗法是该疗养院首次采用的此类治疗方法，包括同时使用包裹法和阴道填塞法。对55名黄体功能正常的女性在月经周期的第18至22天进行该治疗。其中32名使用高温泥浆，23名使用等温泥浆。在41名黄体功能不全的受试女性中，21名使用高温泥浆，20名使用等温泥浆。在所有女性治疗前、治疗后2小时和5小时，完成的放射免疫测定包括：血清中促卵泡生成素（FSH）、促黄体生成素（LH）、孕酮和雌二醇的浓度。此外，采用荧光法测定尿中肾上腺素和去甲肾上腺素的水平，并以每克肌酐计算。其中10名女性在治疗后的前2小时每15分钟测定一次FSH和LH的浓度。对黄体激素功能正常和不全的女性，采用高温或等温泥浆进行的上述治疗均以类似方式导致血清中孕酮和雌二醇浓度短暂升高。尿中肾上腺素和去甲肾上腺素的排泄也显著增加，尤其是在使用高温泥浆后。上述类固醇浓度的升高与促性腺激素浓度的升高无关，但可能是由于它们从卵巢中释放所致。
