Zurnadzhi Iu N, Bogdanova T I, Tron'ko N D, Rybakov S I, Cherniĭ Ia M, Komissarenko I V, Bol'shova E V, Oleĭnik V A, Epshteĭn E V, Shakhmatova V A
Arkh Patol. 1993;55(5):55-60.
Thyroid cancers in children from the affected areas of Ukraine were investigated by means of light (33 cases) and electron (20 cases) microscopy. Statistical data from 25 regions of Ukraine have been analyzed concerning thyroid cancer in patients aged up to 18 years for the period 1981-1990. There is an increase in the number of thyroid cancers in the children of Ukraine from 0.04-0.06 cases in the "pre-chernobyl" period to 0.23 cases per 10(5) children's population in 1990. In the children operated in the Clinic of the Institute of Endocrinology in 1990-1991, severe forms of thyroid lesions with metastases to the lymph nodes were noted. Histopathological studies show prevalence of different variants of papillary cancer with presence of follicular, solid, poorly differentiated areas. Ultrastructural analysis revealed polymorphism of tumour cells, various degrees of their differentiation and functional specialization that point to a mixed multicomponent nature of carcinomas.
通过光学显微镜（33例）和电子显微镜（20例）对来自乌克兰受影响地区儿童的甲状腺癌进行了研究。分析了乌克兰25个地区1981 - 1990年期间18岁以下患者甲状腺癌的统计数据。乌克兰儿童甲状腺癌的数量有所增加，从“切尔诺贝利事故前”时期的每10万儿童中0.04 - 0.06例增加到1990年的每10万儿童中0.23例。在1990 - 1991年于内分泌研究所诊所接受手术的儿童中，发现了伴有淋巴结转移的严重甲状腺病变形式。组织病理学研究显示乳头状癌不同变体的普遍性，伴有滤泡状、实性、低分化区域。超微结构分析揭示了肿瘤细胞的多态性、它们不同程度的分化和功能特化，这表明癌具有混合多成分性质。
