Colombo M P, Forni G
Divisione di Oncologia Sperimentale D, Istituto Nazionale Tumori, Milan, Italy.
Immunol Today. 1994 Feb;15(2):48-51. doi: 10.1016/0167-5699(94)90131-7.
Vaccination with tumor cells that have been engineered to express cytokine genes has been developed in animal models as a novel form of tumor therapy. Mario Colombo and Guido Forni assess the current situation and suggest a way forward.
用经过基因工程改造以表达细胞因子基因的肿瘤细胞进行疫苗接种,已在动物模型中作为一种新型肿瘤治疗方法得以开发。马里奥·科隆博和圭多·福尔尼评估了当前形势并提出了前进方向。